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Download Brain Metastases from Primary Tumors, Volume 2: by M. A. Hayat PDF

By M. A. Hayat

Brain metastases are the commonest malignant tumors of the crucial fearful procedure, but their prevalence seems to be expanding regardless of the development of melanoma cures. whereas a lot is understood approximately fundamental cancers (including fundamental mind tumors), much less paintings has been performed to discover the roots of metastatic disorder. Brain Metastases from fundamental Tumors fills that hole, serving because the first two-part connection with concentration totally on the hyperlink among fundamental cancers and mind metastases. This hyperlink is explored for the most typical melanoma forms – lung, breast, and cancer. also, organic historical past in addition to remedy for CNS metastases is addressed. Age- and gender-related traits also are mentioned, as is using biomarkers for early detection.

  • The in simple terms accomplished reference detailing the hyperlink among basic cancers and mind metastases
  • Aids the objective viewers in settling on the occurrence of mind metastases in sufferers with a major cancer
  • Provides schooling in regards to the capability use of biomarkers for early detection, prognosis and prevention of the unfold of fundamental melanoma to the brain
  • Documents temporal and gender-related traits in mind metastases from different cancers
  • Edited paintings with chapters authored via leaders within the box around the world – the broadest, so much professional assurance available
  • The purely finished reference detailing the hyperlink among fundamental cancers and mind metastases

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Extra info for Brain Metastases from Primary Tumors, Volume 2: Epidemiology, Biology, and Therapy

Example text

Pharm. Res. 29, 770–781. , 2012. Chemotherapy-related cognitive dysfunction. Curr. Neurol. Neurosci. Rep. 12, 267–275. , 2000. Radiosurgery for brain metastases: a score index for predicting prognosis. Int. J. Radiat. Oncol. Biol. Phys. 46, 1155–1161. , 2013. Role of the blood-brain barrier in the formation of brain metastases. Int. J. Mol. Sci. 14, 1383–1411. , 1992. Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice.

Predictive factors for the development of brain metastasis in advanced unresectable metastatic melanoma. Am. J. Clin. Oncol. 34, 603–610. , 2012. Brain metastases free survival differs between breast cancer subtypes. Br. J. Cancer 106, 440–446. , 1993. Surgical treatment of multiple brain metastases. J. Neurosurg. 79, 210–216. , 1995. Reoperation for recurrent metastatic brain tumors. J. Neurosurg. 83, 600–604. , 2013. Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial.

In fact, patients are now being recommended prophylactic cranial irradiation (PCI), radiotherapy to the whole brain typically administered at a lower dose than that used for definitive WBRT. It is hoped that this preemptive radiotherapy will decrease the rates of development of new or recurrent metastasis, especially among patients whose primary tumors are breast cancer, melanoma, or lung cancer, which are associated with early spread to the brain. PCI is considered the standard of care for patients with SCLC.

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